A drive towards preservative-free formulations
Growing concerns about preservative safety and increasing regulatory concerns, especially from the
European Medicines Agency (EMA), are fueling demand for preservative-free formulations — including
nasal spray drug products. This trend is requires formulation without preservatives.
Meeting this rising need for preservative-free products requires specialized capabilities and expertise
to support their complex manufacturing.
Find out how we can bring your preservative-free nasal spray drug product to patients.
Progressing your preservative-free
product seamlessly
Take your nasal product from clinic to
commercial by harnessing our aseptic
nasal filling line.
Our dedicated preservative free filling
line fills and assembles nasal products
in a Grade A environment.
Build and retain investor confidence through the swift transition to clinical trial.
Enhance your nasal spray drug
product manufacturing with our
flexible, preservative-free capabilities,
supporting nasal spray solutions, thin
gels and emulsions.
Our preservative-free filling line also
accommodates multiple types of nasal
spray pumps.
Meeting preservative-free needs with extensive nasal spray expertise
Ensuring quality at every step
Your preservative-free product
deserves the highest quality at
every stage of production, and
we are committed to delivering
just that, leveraging:
- In-line Sterile filtration, vial
washing, and depyrogenation
prior to filling - Extensive environmental
and personnel microbial
monitoring - Robust, validated
cleaning procedures
Safeguarding sterility
For your preservative-free
formulation, sterility is key.
Our in-house sterility
testing, along with ICHcompliant stability chambers
(including Zone IVb), ensures
the quality and safety of
your product throughout
manufacturing, registration
and commercialization.
Leveraging an unmatched
regulatory track record
Ensure that your
preservative-free drug
product meets evolving
regulatory standards with
the support of our in-house
regulatory affairs team
at every step
We work with you to
demonstrate that sterility
and device container-closure
integrity are maintained
throughout the shelf-life
of your product and during
the use of multi-dose formats.
Discover how
Renaissance Lakewood
can simplify the journey
of your preservative-free
nasal spray product.
Ready to streamline your nasal product journey?
With unrivaled expertise and experience in nasal product development and manufacturing, we breathe excellence into nasal delivery.
Find out how we can accelerate timelines to clinic for your next nasal spray product in our whitepaper.
Download the whitepaper
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